Introducción El trasplante renal con donante vivo ocupa el 23 % de los trasplantes en Colombia y la mayoría de los donantes que se evalúan no finalizan el proceso. Objetivo Describir las causas de la no finalización efectiva del proceso de donación de riñón, caracterizando a los donantes vivos de riñón posibles y efectivos evaluados […]
Introduction Non-adherence in kidney transplants is diversely defined. Immunosuppression non-adherence (INA) is the most used definition and has been associated with graft loss and acute rejection. But INA assesses only one fraction of adherence. Therefore, we analyzed the association of a holistic non-adherence definition with transplant outcomes and compared its prediction performance with other definitions.
Introduction The coronavirus 19 disease (COVID-19) increased mortality in organ solid transplant patients due to chronic immunosuppression and significant comorbidity burden. We aim to evaluate patient and graft survival in kidney transplant (KT) recipients who were hospitalized or treated in Intensive Care Units (ICU) after contracting COVID-19. Keywords Kidney Transplantation, COVID-19, Pandemic, Graft Survival, Patient
In-hospital clinical outcomes in kidney transplant recipients with COVID-19 infection Read More »
Introducción Los términos falla intestinal crónica, síndrome de intestino corto (SIC) y nutrición parenteral total son muy frecuentes en la práctica clínica cotidiana. El objetivo de esta guía fue establecer un marco de referencia de práctica clínica basado en el mejor de nivel de evidencia en pacientes con falla intestinal crónica secundaria a síndrome de
Consenso colombiano de Falla Intestinal Crónica en Síndrome de Intestino Corto Read More »
Resumen El desarrollo de la inteligencia artificial (IA), así como la mejora evidente que han tenido las tecnologías digitales en el campo de la salud, obliga a plantearnos dos preguntas importantes que surgen al incorporar la IA como instrumento para una mejora en la calidad de atención. 1) ¿Podrá la IA reemplazar a los médicos?
Antecedentes y objetivo La administración de manitol durante la nefrectomía laparoscópica en el donante vivo ha sido discutida con diversas recomendaciones. El objetivo es evaluar la administración de manitol intraoperatorio en el donante vivo de riñón y la incidencia de función retardada del injerto en el receptor. Métodos Estudio observacional retrospectivo con receptores de riñón
Introduction In renal transplant recipients, compliance with medical therapy is vital. Non-adherence is considered a risk factor for worst outcomes in kidney recipients, with attributed outcomes of 64% for graft loss and 80% for late acute rejection. Most literature defines adherence as self-based immunosuppression compliance but does not consider other relevant factors such as consult
Introduction A complex relationship between donor and recipient characteristics influences kidney transplant (KT) success. A tool developed by Bae S. et al. (Survival Benefit Estimator, SBE) helps estimate post-KT survival. We aim to evaluate the predictive performance of the SBE tool in terms of 5-year patient survival after a kidney transplant. Methods A retrospective cohort
Background The accuracy of the measurement of renal function in potential living kidney donors (PLKD) is essential. Te direct measurement of glomerular fltration rate (mGFR) has been considered the “gold standard.” The estimated GFR (eGFR) with 24- hour urinary creatinine clearance (CrCl) is frequently used because of its availability. We aim to evaluate the correlation
Background Renal operational tolerance is a rare and beneficial state of prolonged renal allograft function in the absence of immunosuppression. The underlying mechanisms are unknown. We hypothesized that tolerance might be driven by inherited protein coding genetic variants with large effect, at least in some patients. Methods We set up a European survey of over
An exome-wide study of renal operational tolerance Read More »
HIGHLIGHTS The COVID-19 vaccination plan of Colombia included several types of these vaccines offering an opportunity for assessing simultaneously differences in humoral response to them among transplant recipients. We found a differential response among vaccines including an absence of humoral response in transplant recipients who received CoronaVac and were been treated with Belatacept. Patients with
Introducción La pandemia por COVID-19 ha causado la muerte de 6,5 millones de personas en el mundo y la donación de órganos se ha visto ampliamente afectada. Esto se refleja en una disminución importante en el número de trasplantes. Colombia no ha sido ajena a dicha problemática. Ante este desafío, el Instituto Nacional de Salud